≥98% HPLC PURITY

Semaglutide

3mg / 10 VIALS

MINDTEK · RESEARCH USE ONLY

RESEARCH USE ONLY COA VERIFIED SOLUTION PHASE

Semaglutide

GLP-1 Receptor Agonist

31-amino-acid GLP-1 analogue with a C18 fatty-diacid side chain conferring extended half-life. Selective GLP-1 receptor agonism modulating insulin secretion, glucagon, and satiety.

MW: 4113.58 Da CAS: 910463-68-2 Per Vial: 3mg Kit: 10 Vials

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1 Vial $110Order

3 Vials Save 19%$99 eaOrder

5 Vials Save 19%$89 eaOrder

10 Vials Best Value$79 eaOrder

Mechanism of Action

Semaglutide is a long-acting GLP-1 receptor agonist derived from human GLP-1 (94% homology) with substitutions that resist DPP-4 degradation. Receptor engagement potentiates glucose-dependent insulin secretion, suppresses glucagon, slows gastric emptying, and reduces energy intake in research models.

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GLP-1 Receptor Agonism

Glucose-dependent insulinotropic signalling and central appetite suppression.

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DPP-4 Resistance

Amino-acid substitution and lipidation extend half-life for sustained receptor exposure.

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Glucoregulatory Effect

Glucagon suppression and delayed gastric emptying documented across independent research groups.

Research Evidence

DATA = directly reported in cited study · INFERENCE = derived · SPECULATION = hypothesis

Knudsen LB & Lau J (2019) Front Endocrinol 10:155DATA

Semaglutide, a lipidated GLP-1 analogue, achieves once-weekly exposure via albumin binding and DPP-4 resistance (DATA).

Marso SP et al. (2016) N Engl J Med 375(19) SUSTAIN-6DATA

Semaglutide reduced cardiovascular events and HbA1c vs. placebo over 104 weeks (DATA).

Wilding JPH et al. (2021) N Engl J Med 384(11) STEP-1DATA

14.9% mean body-weight reduction at 68 weeks vs. placebo in adults without diabetes (DATA).

Certificate of Analysis

Every Mindtek batch is independently tested before release. We were among the first peptide suppliers in Southeast Asia to implement mandatory third-party HPLC verification — a standard, not an exception.

HPLC Purity≥98.0%

Bacterial Endotoxins≤5 EU/mg

Water Content (Karl Fischer)≤8.0%

Peptide Content≥80%

StandardUSP/EP

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Research Protocol Reference

For laboratory research use only — not for human or veterinary use.

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Reconstitution

Add sterile bacteriostatic water (0.9% benzyl alcohol) slowly against the vial wall. Gently swirl — do not vortex. Allow 5 min for complete dissolution.

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Storage

Store solution-phase at -20°C. Post-reconstitution: maintain at 2–8°C, use within 28 days. Protect from light. Avoid repeated freeze-thaw cycles.

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Administration

SubQ or IM administration in standard research protocols. Insulin syringe recommended for precise dosing. Refer to published literature for compound-specific protocols.

Frequently Asked Questions

What is Semaglutide?

Semaglutide is a 31-amino-acid GLP-1 analogue (selective GLP-1 receptor agonist) derived from human GLP-1. Research applications: metabolic, glucoregulatory, and energy-balance studies. Research use only.

How is Mindtek Semaglutide produced?

Synthesised via solid-phase peptide synthesis (SPPS). Each batch: HPLC purity verification (≥99.3%), mass spectrometry identity, endotoxin testing prior to release.

Storage requirements?

Store solution-phase Semaglutide at -20°C. Post-reconstitution with sterile BAC water: 2–8°C, use within 28 days. Avoid repeated freeze-thaw cycles.

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