Learn More
≥98% HPLC PURITY
Sermorelin
5mg / 10 VIALS
MINDTEK · RESEARCH USE ONLY
RESEARCH USE ONLY COA VERIFIED SOLUTION PHASE

Sermorelin

GHRH (1-29) Analogue

Synthetic 29-amino-acid peptide corresponding to the active N-terminus of growth-hormone-releasing hormone (GHRH). Binds pituitary GHRH receptors to stimulate endogenous, feedback-regulated GH secretion.

MW: 3357.9 Da CAS: 86168-78-7 Per Vial: 5mg Kit: 10 Vials
SELECT QUANTITY
1 Vial $65Order
3 Vials Save 9%$59 eaOrder
5 Vials Save 32%$44 eaOrder
10 Vials Best Value$33 eaOrder

Mechanism of Action

Sermorelin reproduces the first 29 residues of GHRH, the minimal sequence for full receptor activity. It engages pituitary GHRH receptors to drive pulsatile GH release that remains under normal somatostatin feedback, distinguishing it from exogenous recombinant GH.

⚡
GHRH Receptor Agonism
Binds pituitary GHRH receptors on somatotrophs.
🔬
Feedback-Regulated GH
Pulsatile GH release preserved under somatostatin control.
🧬
Endogenous GH Axis
Stimulates endogenous GH rather than exogenous replacement.

Research Evidence

DATA = directly reported in cited study · INFERENCE = derived · SPECULATION = hypothesis

Prakash A & Goa KL (1999) BioDrugs 12(2)DATA
Reviewed sermorelin (GRF 1-29) for the diagnosis and treatment of GH deficiency; the N-terminal 29 residues confer full GHRH activity (DATA).
Ishida J et al. (2020) JCSM Rapid Commun 3(1)DATA
Positions GHRH analogues including sermorelin within the GH-secretagogue class and mechanism landscape (DATA).
Mechanistic synthesis · GHRH axisDATA
Feedback-regulated GH release is the rationale for research interest versus direct GH administration (INFERENCE).

Certificate of Analysis

Every Mindtek batch is independently tested before release. We were among the first peptide suppliers in Southeast Asia to implement mandatory third-party HPLC verification — a standard, not an exception.

HPLC Purity≥98.0%
Bacterial Endotoxins≤5 EU/mg
Water Content (Karl Fischer)≤8.0%
Peptide Content≥80%
StandardUSP/EP

Research Protocol Reference

For laboratory research use only — not for human or veterinary use.

💧
Reconstitution
Add sterile bacteriostatic water (0.9% benzyl alcohol) slowly against the vial wall. Gently swirl — do not vortex. Allow 5 min for complete dissolution.
🧊
Storage
Store solution-phase at -20°C. Post-reconstitution: maintain at 2–8°C, use within 28 days. Protect from light. Avoid repeated freeze-thaw cycles.
📐
Administration
SubQ or IM administration in standard research protocols. Insulin syringe recommended for precise dosing. Refer to published literature for compound-specific protocols.

Frequently Asked Questions

What is Sermorelin?
Sermorelin is a synthetic 29-amino-acid peptide (the active N-terminal 1-29 fragment of GHRH) corresponding to the GHRH N-terminus. Research applications: growth-hormone axis and endocrine research. Research use only.
How is Mindtek Sermorelin produced?
Synthesised via solid-phase peptide synthesis (SPPS). Each batch: HPLC purity verification (≥99.3%), mass spectrometry identity, endotoxin testing prior to release.
Storage requirements?
Store solution-phase Sermorelin at -20°C. Post-reconstitution with sterile BAC water: 2–8°C, use within 28 days. Avoid repeated freeze-thaw cycles.

Ready to Order Sermorelin?

Mindtek ships solution-phase, independently verified research compounds to qualified researchers globally. First in Southeast Asia.

Place an Order Research Hub