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≥98% HPLC PURITY
Melanotan-2
10mg / 10 VIALS
MINDTEK · RESEARCH USE ONLY
RESEARCH USE ONLY COA VERIFIED SOLUTION PHASE

Melanotan-2

Melanocortin Receptor Agonist

Cyclic synthetic analogue of alpha-MSH. Non-selective melanocortin-receptor (MC1R-MC5R) agonist studied for melanogenesis and MC4R-mediated pathways in research models.

MW: 1024.2 Da CAS: 121062-08-6 Per Vial: 10mg Kit: 10 Vials
SELECT QUANTITY
1 Vial $60Order
3 Vials Save 8%$55 eaOrder
5 Vials Save 18%$49 eaOrder
10 Vials Best Value$45 eaOrder

Mechanism of Action

Melanotan-2 is a cyclic lactam analogue of alpha-MSH that activates melanocortin receptors, notably MC1R (melanogenesis) and MC4R (central appetite and sexual-function pathways). Its cyclisation confers metabolic stability and prolonged receptor activity in research models.

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MC1R Activation
Stimulates eumelanin synthesis in melanocytes.
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MC4R Signalling
Central melanocortin pathway engagement.
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Metabolic Stability
Cyclic lactam structure resists enzymatic degradation.

Research Evidence

DATA = directly reported in cited study · INFERENCE = derived · SPECULATION = hypothesis

Dorr RT et al. (1996) Life Sci 58(20)DATA
Melanotan-II induced melanogenesis in a controlled human research study (DATA).
Wessells H et al. (1998) J Urol 160(2)DATA
MT-II demonstrated melanocortin-receptor-mediated effects in a research setting (DATA).
Mechanistic synthesis · melanocortin axisDATA
Broad MC-receptor agonism is the rationale for research interest (INFERENCE).

Certificate of Analysis

Every Mindtek batch is independently tested before release. We were among the first peptide suppliers in Southeast Asia to implement mandatory third-party HPLC verification — a standard, not an exception.

HPLC Purity≥98.0%
Bacterial Endotoxins≤5 EU/mg
Water Content (Karl Fischer)≤8.0%
Peptide Content≥80%
StandardUSP/EP

Research Protocol Reference

For laboratory research use only — not for human or veterinary use.

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Reconstitution
Add sterile bacteriostatic water (0.9% benzyl alcohol) slowly against the vial wall. Gently swirl — do not vortex. Allow 5 min for complete dissolution.
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Storage
Store solution-phase at -20°C. Post-reconstitution: maintain at 2–8°C, use within 28 days. Protect from light. Avoid repeated freeze-thaw cycles.
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Administration
SubQ or IM administration in standard research protocols. Insulin syringe recommended for precise dosing. Refer to published literature for compound-specific protocols.

Frequently Asked Questions

What is Melanotan-2?
Melanotan-2 is a cyclic alpha-MSH analogue (cyclic Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-NH2) a cyclic melanocortin-receptor agonist. Research applications: melanogenesis and melanocortin-pathway studies. Research use only.
How is Mindtek Melanotan-2 produced?
Synthesised via solid-phase peptide synthesis (SPPS). Each batch: HPLC purity verification (≥99.3%), mass spectrometry identity, endotoxin testing prior to release.
Storage requirements?
Store solution-phase Melanotan-2 at -20°C. Post-reconstitution with sterile BAC water: 2–8°C, use within 28 days. Avoid repeated freeze-thaw cycles.

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