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≥98% HPLC PURITY
AOD-9604
5mg / 10 VIALS
MINDTEK · RESEARCH USE ONLY
RESEARCH USE ONLY COA VERIFIED SOLUTION PHASE

AOD-9604

Lipolytic GH Fragment (176-191 analogue)

Modified C-terminal fragment of human growth hormone (hGH 177-191) with an added N-terminal tyrosine. Stimulates lipolysis and fat oxidation without the glucose or growth effects of full-length GH in research models.

MW: 1815.08 Da CAS: 221231-10-3 Per Vial: 5mg Kit: 10 Vials
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1 Vial $65Order
3 Vials Save 9%$59 eaOrder
5 Vials Save 15%$55 eaOrder
10 Vials Best Value$45 eaOrder

Mechanism of Action

AOD-9604 is a synthetic analogue of the hGH C-terminal lipolytic domain. It stimulates lipolysis and inhibits lipogenesis via beta3-adrenergic-linked pathways in adipose tissue while, unlike intact GH, leaving IGF-1, glucose tolerance, and longitudinal growth unaffected in research models.

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Lipolytic Domain
Reproduces the fat-mobilising C-terminus of growth hormone.
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Beta3-Adrenergic Pathway
Fat oxidation linked to beta3-AR signalling in adipocytes.
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GH-Effect Dissociation
No IGF-1 rise or glucose intolerance in research models.

Research Evidence

DATA = directly reported in cited study · INFERENCE = derived · SPECULATION = hypothesis

Heffernan MA et al. (2001) Endocrinology 142(12)DATA
hGH and AOD-9604 increased fat oxidation and reduced body weight in obese mice; the effect was attenuated in beta3-AR knockouts, with IGF-1 unchanged (DATA).
Ng FM & Bornstein J (1978) Am J Physiol 234(5)DATA
Synthetic C-terminal GH fragments retained the lipolytic activity of intact hGH, dissociated from anabolic effects (DATA).
Mechanistic synthesis · beta3-AR lipolysisDATA
Dissociation of fat oxidation from GH-anabolic effects is the rationale for research interest (INFERENCE).

Certificate of Analysis

Every Mindtek batch is independently tested before release. We were among the first peptide suppliers in Southeast Asia to implement mandatory third-party HPLC verification — a standard, not an exception.

HPLC Purity≥98.0%
Bacterial Endotoxins≤5 EU/mg
Water Content (Karl Fischer)≤8.0%
Peptide Content≥80%
StandardUSP/EP

Research Protocol Reference

For laboratory research use only — not for human or veterinary use.

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Reconstitution
Add sterile bacteriostatic water (0.9% benzyl alcohol) slowly against the vial wall. Gently swirl — do not vortex. Allow 5 min for complete dissolution.
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Storage
Store solution-phase at -20°C. Post-reconstitution: maintain at 2–8°C, use within 28 days. Protect from light. Avoid repeated freeze-thaw cycles.
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Administration
SubQ or IM administration in standard research protocols. Insulin syringe recommended for precise dosing. Refer to published literature for compound-specific protocols.

Frequently Asked Questions

What is AOD-9604?
AOD-9604 is a modified C-terminal fragment of human growth hormone (hGH(177-191) with an N-terminal tyrosine) derived from the growth-hormone lipolytic domain. Research applications: adipose-metabolism and lipolysis research. Research use only.
How is Mindtek AOD-9604 produced?
Synthesised via solid-phase peptide synthesis (SPPS). Each batch: HPLC purity verification (≥99.3%), mass spectrometry identity, endotoxin testing prior to release.
Storage requirements?
Store solution-phase AOD-9604 at -20°C. Post-reconstitution with sterile BAC water: 2–8°C, use within 28 days. Avoid repeated freeze-thaw cycles.

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