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≥98% HPLC PURITY
Kisspeptin-10
100mg / 10 VIALS
MINDTEK · RESEARCH USE ONLY
RESEARCH USE ONLY COA VERIFIED SOLUTION PHASE

Kisspeptin-10

KISS1R (GPR54) Agonist

Decapeptide fragment of kisspeptin (Kisspeptin-10). Potent agonist of the KISS1 receptor (GPR54), a proximal trigger of GnRH release and the reproductive endocrine axis in research models.

MW: 1302.5 Da CAS: 374675-21-5 Per Vial: 100mg Kit: 10 Vials
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Mechanism of Action

Kisspeptin-10 binds KISS1R (GPR54) on hypothalamic GnRH neurons, stimulating GnRH secretion and downstream LH/FSH release. It sits upstream of the reproductive axis and is studied as a physiological gatekeeper of puberty and fertility signalling in research models.

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KISS1R / GPR54 Agonism
Agonism at the kisspeptin receptor on GnRH neurons.
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GnRH Release
Upstream trigger of gonadotropin (LH/FSH) secretion.
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Reproductive Axis
Central regulator of the HPG axis in research models.

Research Evidence

DATA = directly reported in cited study · INFERENCE = derived · SPECULATION = hypothesis

de Roux N et al. (2003) Proc Natl Acad Sci 100(19)DATA
GPR54 loss-of-function disrupts the reproductive axis, establishing kisspeptin signalling as essential (DATA).
Dhillo WS et al. (2005) J Clin Endocrinol Metab 90(12)DATA
Kisspeptin increased LH, FSH, and testosterone in a human research study (DATA).
Mechanistic synthesis · HPG axisDATA
Upstream control of GnRH is the rationale for research interest (INFERENCE).

Certificate of Analysis

Every Mindtek batch is independently tested before release. We were among the first peptide suppliers in Southeast Asia to implement mandatory third-party HPLC verification — a standard, not an exception.

HPLC Purity≥98.0%
Bacterial Endotoxins≤5 EU/mg
Water Content (Karl Fischer)≤8.0%
Peptide Content≥80%
StandardUSP/EP

Research Protocol Reference

For laboratory research use only — not for human or veterinary use.

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Reconstitution
Add sterile bacteriostatic water (0.9% benzyl alcohol) slowly against the vial wall. Gently swirl — do not vortex. Allow 5 min for complete dissolution.
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Storage
Store solution-phase at -20°C. Post-reconstitution: maintain at 2–8°C, use within 28 days. Protect from light. Avoid repeated freeze-thaw cycles.
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Administration
SubQ or IM administration in standard research protocols. Insulin syringe recommended for precise dosing. Refer to published literature for compound-specific protocols.

Frequently Asked Questions

What is Kisspeptin-10?
Kisspeptin-10 is a decapeptide fragment of kisspeptin (Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2) the active C-terminal decapeptide of kisspeptin. Research applications: reproductive-endocrinology and HPG-axis studies. Research use only.
How is Mindtek Kisspeptin-10 produced?
Synthesised via solid-phase peptide synthesis (SPPS). Each batch: HPLC purity verification (≥99.3%), mass spectrometry identity, endotoxin testing prior to release.
Storage requirements?
Store solution-phase Kisspeptin-10 at -20°C. Post-reconstitution with sterile BAC water: 2–8°C, use within 28 days. Avoid repeated freeze-thaw cycles.

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