Learn More
≥98% HPLC PURITY
PT-141
10mg / 10 VIALS
MINDTEK · RESEARCH USE ONLY
RESEARCH USE ONLY COA VERIFIED SOLUTION PHASE

PT-141

PT-141 (Bremelanotide)

Melanocortin receptor agonist. MC3R/MC4R activation for sexual function and energy homeostasis research.

MW: 1025.2 Da CAS: 189691-06-3 Per Vial: 10mg Kit: 10 Vials
SELECT QUANTITY
1 Vial $55Order
3 Vials Save 11%$49 eaOrder
5 Vials Save 18%$45 eaOrder
10 Vials Best Value$34 eaOrder

Mechanism of Action

PT-141 is a cyclic heptapeptide melanocortin receptor agonist (MC3R and MC4R). Unlike PDE5 inhibitors, PT-141 acts centrally via hypothalamic melanocortin pathways. Downstream dopaminergic and oxytocin system modulation linked to sexual motivation circuits.

⚡
MC3R/MC4R Agonism
Primary receptor engagement pathway confirmed in vitro and in vivo.
🔬
Hypothalamic Melanocortin Pathway
Downstream signalling cascade activating repair and regenerative gene expression.
🧬
Dopaminergic-Oxytocin Modulation
Tertiary effect pathway documented across multiple independent research groups.

Research Evidence

DATA = directly reported in cited study · INFERENCE = derived · SPECULATION = hypothesis

Diamond LE et al. (2004) J Sex Med 1(1)DATA
PT-141 produced statistically significant improvements in erectile response vs. placebo in Phase 2 trial (p<0.001, DATA).
Kingsberg SA et al. (2019) Obstet Gynecol 134(5)DATA
Bremelanotide demonstrated significant improvement in satisfying sexual events in premenopausal women with HSDD (Phase 3, p<0.001, DATA).
Pfaus JG et al. (2007) Pharmacol Biochem Behav 86(1)DATA
Melanocortin receptor activation enhanced sexual motivation in female rodent models via hypothalamic circuits (DATA).

Certificate of Analysis

Every Mindtek batch is independently tested before release. We were among the first peptide suppliers in Southeast Asia to implement mandatory third-party HPLC verification — a standard, not an exception.

HPLC Purity≥98.0%
Bacterial Endotoxins≤5 EU/mg
Water Content (Karl Fischer)≤8.0%
Peptide Content≥80%
StandardUSP/EP

Research Protocol Reference

For laboratory research use only — not for human or veterinary use.

💧
Reconstitution
Add sterile bacteriostatic water (0.9% benzyl alcohol) slowly against the vial wall. Gently swirl — do not vortex. Allow 5 min for complete dissolution.
🧊
Storage
Store solution-phase at -20°C. Post-reconstitution: maintain at 2–8°C, use within 28 days. Protect from light. Avoid repeated freeze-thaw cycles.
📐
Administration
SubQ or IM administration in standard research protocols. Insulin syringe recommended for precise dosing. Refer to published literature for compound-specific protocols.

Frequently Asked Questions

What is PT-141?
PT-141 (bremelanotide) is a cyclic melanocortin peptide acting on MC3R/MC4R. Acts centrally via hypothalamic pathways. FDA-approved as Vyleesi® for HSDD. Mindtek supplies research-grade PT-141 for laboratory investigation only.
How does PT-141 differ from PDE5 inhibitors?
PT-141 operates centrally via melanocortin receptors, independent of NO-cGMP-PDE5 pathway. Studied for cases where vascular-acting compounds are contraindicated.
Purity of Mindtek PT-141?
Batch-verified ≥98.16% purity by HPLC. Full CoA available on request.

Ready to Order PT-141?

Mindtek ships solution-phase, independently verified research compounds to qualified researchers globally. First in Southeast Asia.

Place an Order Research Hub