RESEARCH USE ONLY COA VERIFIED SOLUTION PHASE

NA-Selank

NA-Selank (N-Acetyl Selank)

N-acetylated heptapeptide anxiolytic. GABA-A potentiation and IL-6 modulation in anxiety and stress research models.

MW: 799.93 Da CAS: 129954-34-3 Per Vial: 30mg Kit: 10 Vials

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Mechanism of Action

NA-Selank modulates the GABAergic system via allosteric GABA-A potentiation, producing anxiolytic effects without sedation or dependence. Upregulates BDNF and SERT. Immunomodulatory via IL-6/IL-4 ratio normalisation and enkephalin peptidase inhibition.

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GABA-A Allosteric Potentiation

Primary receptor engagement pathway confirmed in vitro and in vivo.

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BDNF/SERT Upregulation

Downstream signalling cascade activating repair and regenerative gene expression.

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Enkephalinase Inhibition

Tertiary effect pathway documented across multiple independent research groups.

Research Evidence

DATA = directly reported in cited study · INFERENCE = derived · SPECULATION = hypothesis

Semenova TP et al. (2010) Neurosci Behav Physiol 40(2)DATA

Selank demonstrated consistent anxiolytic effect in open-field and plus-maze models at 300 mcg/kg without sedative profile (DATA).

Inozemtseva LS et al. (2008) Peptides 29(9)DATA

Selank modulated IL-6/IL-4 cytokine balance and upregulated BDNF expression in hippocampus vs. stressed controls (DATA).

Volkova A et al. (2016) Mol Biol 50DATA

RNA analysis: Selank upregulated 36 genes including SERT and neuropeptide precursors after 24h administration (DATA).

Certificate of Analysis

Every Mindtek batch is independently tested before release. We were among the first peptide suppliers in Southeast Asia to implement mandatory third-party HPLC verification — a standard, not an exception.

HPLC Purity≥98.0%

Bacterial Endotoxins≤5 EU/mg

Water Content (Karl Fischer)≤8.0%

Peptide Content≥80%

StandardUSP/EP

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Research Protocol Reference

For laboratory research use only — not for human or veterinary use.

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Reconstitution

Add sterile bacteriostatic water (0.9% benzyl alcohol) slowly against the vial wall. Gently swirl — do not vortex. Allow 5 min for complete dissolution.

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Storage

Store solution-phase at -20°C. Post-reconstitution: maintain at 2–8°C, use within 28 days. Protect from light. Avoid repeated freeze-thaw cycles.

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Administration

SubQ or IM administration in standard research protocols. Insulin syringe recommended for precise dosing. Refer to published literature for compound-specific protocols.

Frequently Asked Questions

What is NA-Selank?

N-acetylated form of Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro), a synthetic tuftsin analogue. Research: anxiety, stress response, immune modulation, BDNF upregulation. Research use only.

Does NA-Selank cause sedation?

Research models show Selank/NA-Selank anxiolytic activity without sedation, motor impairment, or withdrawal — distinct from benzodiazepines (Semenova et al. 2010, DATA).

Dose per vial?

30mg per vial. Supplied in 10-vial kits.

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