≥98% HPLC PURITY

Thymosin Alpha-1

5mg / 10 VIALS

MINDTEK · RESEARCH USE ONLY

RESEARCH USE ONLY COA VERIFIED SOLUTION PHASE

Thymosin Alpha-1

Thymic Immunomodulatory Peptide

28-amino-acid N-terminally acetylated thymic peptide (thymalfasin). Modulates innate and adaptive immunity via Toll-like-receptor signalling and T-cell maturation in research models.

MW: 3108.3 Da CAS: 62304-98-7 Per Vial: 5mg Kit: 10 Vials

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1 Vial $85Order

3 Vials Save 12%$75 eaOrder

5 Vials Save 19%$69 eaOrder

10 Vials Best Value$59 eaOrder

Mechanism of Action

Thymosin alpha-1 signals through Toll-like receptors (TLR2/TLR9) on dendritic cells and promotes T-cell differentiation toward Th1 cytokine profiles. It enhances antigen presentation and NK-cell activity in research models, acting as an immune-restorative rather than a direct effector.

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TLR Signalling

Engages TLR2/TLR9 on antigen-presenting cells.

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T-cell Maturation

Promotes Th1 differentiation and IL-2 / IFN-gamma profiles.

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Innate Immunity

Enhances NK-cell and dendritic-cell activity in research models.

Research Evidence

DATA = directly reported in cited study · INFERENCE = derived · SPECULATION = hypothesis

Garaci E et al. (2007) Ann N Y Acad Sci 1112DATA

Thymosin alpha-1 modulated immune responses across infectious and oncologic research models (DATA).

Romani L et al. (2004) Blood 103(11)DATA

Thymosin alpha-1 activated dendritic cells via TLR9 to drive Th1 antifungal resistance in research models (DATA).

Mechanistic synthesis · TLR / T-cell axisDATA

Immune-restorative signalling rather than direct effector action is the rationale for research interest (INFERENCE).

Certificate of Analysis

Every Mindtek batch is independently tested before release. We were among the first peptide suppliers in Southeast Asia to implement mandatory third-party HPLC verification — a standard, not an exception.

HPLC Purity≥98.0%

Bacterial Endotoxins≤5 EU/mg

Water Content (Karl Fischer)≤8.0%

Peptide Content≥80%

StandardUSP/EP

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Research Protocol Reference

For laboratory research use only — not for human or veterinary use.

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Reconstitution

Add sterile bacteriostatic water (0.9% benzyl alcohol) slowly against the vial wall. Gently swirl — do not vortex. Allow 5 min for complete dissolution.

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Storage

Store solution-phase at -20°C. Post-reconstitution: maintain at 2–8°C, use within 28 days. Protect from light. Avoid repeated freeze-thaw cycles.

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Administration

SubQ or IM administration in standard research protocols. Insulin syringe recommended for precise dosing. Refer to published literature for compound-specific protocols.

Frequently Asked Questions

What is Thymosin Alpha-1?

Thymosin Alpha-1 is a 28-amino-acid acetylated thymic peptide (Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-...) the naturally occurring thymic peptide. Research applications: immunology, immune-restoration, and vaccine-adjuvant studies. Research use only.

How is Mindtek Thymosin Alpha-1 produced?

Synthesised via solid-phase peptide synthesis (SPPS). Each batch: HPLC purity verification (≥99.3%), mass spectrometry identity, endotoxin testing prior to release.

Storage requirements?

Store solution-phase Thymosin Alpha-1 at -20°C. Post-reconstitution with sterile BAC water: 2–8°C, use within 28 days. Avoid repeated freeze-thaw cycles.

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